The Spectacular Spider-Man/Recap/S1/E03 Natural Selection

Everything About Fiction You Never Wanted to Know.
I've made...a terrible...mistake.
—Curt Connors right before his Painful Transformation into the Lizard

During his patrol, Spider-Man stops a group of thieves who are breaking into a bakery. Peter manages to snap some pictures to try and sell to the Daily Bugle. He happily leaves and makes it back home in time for his curfew (although Aunt May points out that he only made it back with seconds to spare), but discovers after developing his photos that he has messed them up.

Meanwhile Dr. Curt Connors injects himself with the lizard serum (that had unknowingly been amplified by Electro) to regrow his arm. He awakes in pain, and his arm indeed regrows, but knowing that he experimented on himself, his wife, Martha, is furious that Curt used an untested formula on himself. Curt brushes away her worries and rejoices with Billy.

At school, Peter is attacked with water balloons by Flash Thompson and Kenny "King Kong" McFarlane, which he dodges until he realizes it might reveal his secret identity as Spider-Man. Gwen steps in and gets everyone to laugh at Flash instead by taunting him about a foul-up during a past football game. Gwen and Peter go to the Connors lab, and Peter begins complaining about his problems, only for Gwen to tell him to stop pitying himself. They enter the lab, thinking they're going to help Eddie clean up from the battle with Electro.

Curt reveals that his arm has grown back and they celebrate until they realize scales are growing on his arm and back, determining that the reptilian half of his brain his taking over and Curt is slowly regressing. Going over Curt's notes, the group decides that a gene cleanser is the way to go. This new formula will block out any non-human DNA and keep Curt human. Peter muses that this could also take away his spider-powers, before he realizes that Billy has overheard everything. Peter tries to comfort Billy, but his speech about how his father will always love Billy is interrupted by Curt's cries of pain. Horrified, Curt admits that he's made a mistake as his mutation accelerates and he transforms into the Lizard. Martha tries to communicate with him, but Curt's brain is now primal, and he trashes the lab and flees.

While Eddie goes in pursuit, Peter pulls the "Aunt May will ground me" excuse and goes after Connors as Spider-Man, tracking him to Grand Central Station. Trying again in vain to communicate with him, Spider-Man and the Lizard tackle each other into a subway tunnel where the Lizard bashes Spider-Man's hand with his powerful tail. Hastily webbing up his hand, Spider-Man pursues the Lizard along a train car, but the Lizard pushes him through the ceiling and into the car. Dazed, Spider-Man's head is nearly bitten off when a spunky old lady whacks the Lizard with her handbag. Distracting the Lizard, and buying Spider-Man time to regain his senses and shove the Lizard back outside of the car where they continue fighting. Finally, Spider-Man falls off the train, and tries to catch the train with a web. Unfortunately, he hits the Lizard's tail with the webline, which the Lizard rips through and Spider-Man tumbles to the tunnel floor as the Lizard escapes.

Martha and Gwen finish the gene cleanser. Martha points out that the Lizard's hide is too thick to inject it, so it will have to be administered orally. Spider-Man returns to the lab at this point and volunteers to administer the cure. Conveniently, Eddie calls in and informs them that the Lizard is prowling around the Bronx Zoo. Spider-Man takes off in pursuit with a vial of the cleanser. Martha plans to follow and leave Gwen with Billy, but Gwen discovers that Billy is gone, apparently having listened in on the phone call.

Spider-Man meets up with Brock who tells him that the Lizard has gone into the World of Reptiles building. After mistakenly wrestling an alligator, Spider-Man is attacked by the Lizard and nearly drowns but is saved by another alligator distracting the Lizard. The Lizard throws Spider-Man back up to the surface, and Eddie to pulls him out. They come up with a plan to trick him into the polar bear pond. Eddie volunteers himself as bait and finds himself being chased by the Lizard right into the trap. They almost succeed when the Lizard is alerted by Spider-Man's cellphone ringing. The Lizard and Spider-Man fight some more, and then Billy shows up and tries to talk some sense into his father. The Lizard is about to snap Billy up, but Spider-Man leaps in to get the Lizard into the pond. Spider-Man pours the cleanser into the Lizard's mouth, using Billy's skateboard to keep it open wide. Thankfully, the cleanser is a success, and Curt returns to normal, his arm lost once more. And off in the distance, a webbed up camera flashes.

The next day, Peter gets the Lizard photos published in the Bugle and gets the money he needs. However, when Gwen, Eddie, and the Connors' find out, they are outraged that he ran off simply to take pictures. Although Curt is forgiving, considering his own fault in the mess, Martha tells Peter that he has lost her trust and fires him from the internship. Just after Peter leaves, an unseen web-line grabs another vial of gene cleanser. When Peter returns home, he contemplates taking it to get rid of his powers, but decides against it and hides it in his room.

This episode provides examples of:

Curt: Some lizards regenerate lost limbs.
Martha: And some lizards stick to walls and eat raw meat!

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