Jill Trent, Science Sleuth (webcomic)
TG Comics' Jill Trent, She-Sir Science Sleuth: The Remix Comic
Original Jill Trent stories have been recaptioned and presented as 1940s precursors to the fictitious TG Comics Jet Dream feature.
In these stories, heroine Jill Trent was once a male janitor named Jim Trent, who was transformed by exposure to the strange element Femavium into a girl -- but a girl who still has the spinal fluid of a man! When the atoms of Jill's Femavium-enhanced blood were mixed with her "Man-Fluid," the interaction gave her brain cells with the proportional density of 58 girls. Together with her fiancée Daisy, she uses her newfound she-science abilities to fight crime!