Drake and Josh/Heartwarming

"Josh: So... Friends?
 * The Heel Face Turn of the embittered Officer Gilbert in the Christmas Special after the brothers give him a "sweet monkey" as a gift despite his repeated acts to ensure the boys will go to jail.
 * In a Meta example, the mere existence of "Merry Christmas, Drake & Josh" is a Real Life CMOA - Josh Peck & Drake Bell are close friends in real life, and wanted to work together again, so went to Dan Schneider and pointed out that the show never did a Christmas episode, so they should do one so that the fans had something they could watch every year.
 * This dialogue from the Pilot episode

Drake: Pft. We're not friends.



Drake: We're brothers."

"Josh: Wanna get back together?
 * In the episode where the boys get suspiscious of Megan's new boyfriend, who, as it turns out, was cheating on Megan. The boys try to teach him a lesson, not knowing that he knew kung fu. Megan thanks Drake and Josh for what they did. Before leaving, she gives them both a kiss on the cheek.
 * And then tells them both she loves them.
 * In the episode "#1 Fan", one of Megan's friends in her campfire troop gets a crush on Drake and won't leave him alone. When she finally takes it too far, he yells at her for it and breaks her heart. Later on, when Drake is waiting to perform on the radio, he reads an apology card Wendy slipped him and feels bad about what he said, so he cancels his performance and goes back home to sing a song for her (which she'd told him earlier was her dream). When he finishes the song, she hugs him and he lets her keep the guitar pick (he gave it to her earlier and she gave it back with the card).
 * When Josh and Mindy get together and then finally kiss in "Mindy's Back".
 * When Josh and Mindy get back together for good in "Really Big Shrimp".

Mindy: Okay... but I get to be the girlfriend."

"Drake: Man, I'm sorry I made you late for your exam, I'm sorry I ran over your bike! I'm sorry I'm probably the worst brother in the world and you're way better off without me. And I need you more than you need me, I need you way more than you need me! I just-I just... I'm sorry Josh... I'm sorry..."
 * In "Josh is Done", after Drake gets out of the chemical shower and is about to leave the classroom


 * Josh refuses to go after him immediately, but gets Drake into a ping-pong game at the end of the episode and the two are close again.
 * A more subtle moment here - the boys extremely strict teacher, who had around a minute earlier said that he didn't care about his students's personal problems, asks Josh if he wants to go after Drake.
 * The final scene of "Really Big Shrimp" has Drake and Josh fighting over the last piece of shrimp left in their room. What makes this really Heartwarming? The scene quickly changes to a scene from the Amanda Show where Drake and Josh also fight over a piece of shrimp. How touching that they would remember that.
 * Drake taking the fall for Josh at the movie theater so that Josh would keep the job he really loved.