Raising Hope/WMG

Hope will inherit the 'serial killing' gene.
In "Dead Tooth" the only thing that makes Hope laugh is making fun of people. Also, if it's not literally done, it'll be 'played with'.
 * The episode "Killer Hope" will apparently involve Hope getting a mean streak at daycare and the Chances fearing this.

Lucy is still out there
Maybe she has a twin sister who took her place for the execution. Or something. It doesn't matter, what matters is that she can still come back to kill Jimmy.
 * She was probably recruited by the government and is being forcibly trained as an assassin. After all there's no way they would execute the mother of a six month old baby.
 * Actually confirmed in part one of the season two finale - Lucy's still alive somehow.

Greg Garcia is a Troper, or a fan of TV Tropes.
Since every WMG posted so far has basically become canon.

Lucy is still out there AGAIN
They did it once and she's more likely to survive the

Lucys ghost will haunt the Chances
And Possess Maw Maw

Lucy is The Devil, or an incarnation of him.
She survived getting electrocuted lethally, ran away from the afterlife, she's hotter than Hell, oh, and her name is Lucy