Fanboys/YMMV

The Film

 * Crowning Moment of Funny: Windows finds out that his online girlfriend is really . His response?
 * "I'm, I can score anything"
 * Hutch asking the Trekkies what "I'm going to die a virgin" is in Klingon, and one of them responding in fluent Klingon.
 * Crowning Music of Awesome: Provided by Rush.

The Webcomic

 * Accidenta Nightmare Fuel: You will never see Miyamoto-san the same way.
 * Growing the Beard: The comic was discovered by Something Awful, which critically slammed it into the ground for various reasons. Scott read through the responses, then went away for a while afterwards. When he came back the whole comic was drastically improvement, demonstrating how he took the complaints to heart. Since then the comic has been received very warmly.
 * Memetic Mutation: Paul entering the house and interrupting SOMETHING going on before slamming the door has become the punchline to many a webcomic edit (including a number from Awkward Zombie). The latest in the line is a Portal 2 parody.