Panty & Stocking with Garterbelt/Tear Jerker


 * Panty and Stocking With Garterbelt has one, surprisingly. In Ghost: the Phantom of Daten City, Stocking falls head-over-heels in love with a Ghost. A rude, lazy, disgusting ghost who keeps trying to get rid of her, even though she insists they're meant to be together. When she thinks her being an angel might be getting in the way of their relationship, she turns her back on Heaven and tries to run away with him. Panty tries to put a stop to it, but the Ghost interrupts her to propose to Stocking.  The shot of Stocking standing there in the snow while the church bells ringing is incredibly depressing, not to mention seeing the engagement ring in her room.
 * If you follow the Wild Mass Guessing theory that the end credits show how Panty and Stocking's mortal selves died, they could be one, despite the happy smiles of the bobble-headed chibi characters. The ending credits show them being attacked by a monster, strapped under a descending circular saw, and attacked by vultures in the desert, before ascending to Heaven, all to the tune of Mitsunori Ikeda's "Fallen Angel", a tear-jerking song in itself.
 * The Shoot the Shaggy Dog moment at the end of Pulp Addiction counts in typical PSG fashion.
 * The fact that the creator has left Gainax to make his own studio, marks as a Tear Jerker of itself. Combined with the fact of What GAINAX makes now, that we will never see GAINAX make something this awesome ever again.